Instrument Snapshot
With many laser line options, the Zeiss LSM 880 NLO offers up to 7 excitation wavelengths. Samples are protected from photo toxicity and photo bleaching with low laser power observed by the highly sensitive GaAsP spectral detector.
Paired with the Airyscan module, fast events are captured with higher quality, 4x times faster than standard imaging. The system includes additional software modules for controlled region-of-interest scanning, deconvolution, physiology experiments, performing FRAP and control for the motorized stage to allow stitching together images from multiple fields of view into one larger image (montage), as well as visiting multiple sites during a time lapse acquisition.
Reach out to our core facility in Boston with any questions at cils-core@northeastern.edu.
Features
Laser line: 405, 458, 488, 514, 561, 594, 640 nm
NIR Laser: tunable line (680-1300 nm); fixed line -1045 nm
Objective: 10×, 20×, 20×, 40×, 20×-CLARITY
Multi-photon imaging
Spectral Unmixing
Rates
Internal NU
$50/hr
External Academia
$70/hr
Industry
$90/hr
Carl Zeiss Microscopy Online Campus
Education in Microscopy and Digital Imaging
Other Instruments
Beckman Coulter CytoFLEX S Flow Cytometer
NU user: $40/hr; Academia: $70/hr; Industry: $130/hr
4 laser lines: 405, 488, 561, 638
13 color detection
Can load tube or various well plates for analysis
Violet side scatter for small particle detection
Able to interface experiment design into SRT sorter
Visualsonics Vevo F2 Ultrasounds
NU user: $60/h; Academia: $110/h; Industry: $140/h
UHF57x, UHF29x, P10 transducer probes
Prerequisite: Bioraft Biosafety Training
Bruker BioSpec 3T MRI
NU user: $30/hr; Academia: $150/hr; Industry: $200/hr
Automated animal positioning
Multimodal rat/mouse cradle
Two body volume coils for rat/mouse
SAII 1030 monitoring/gating module
Localized MR Spectroscopy
Prerequisite: Bioraft High Magnetic Fields Safety Training
Our facility
Interdisciplinary Science and Engineering Complex
ISEC 080, 805 Columbus Ave, Boston, MA, 02115