Publications

2022

Usability of Deep Learning Pipelines for 3D Nuclei Identification with Stardist and Cellpose
Hypoxia Inhibits the Cardiac IK1 Current through SUMO Targeting Kir2.1 Activation by PIP2
Charge-Based Drug Delivery to Cartilage: Hydrophobic and not Electrostatic Interactions are the Dominant Cause of Competitive Binding of Cationic Carriers in Synovial fluid
Denoising Multiplexed Microscopy Images in N-Dimensional Spectral Space
Cationic Peptide Carriers Enable Long Term Delivery of Insulin-Like Growth Factor-1 to Suppress Osteoarthritis-Induced Matrix Degradation
Targeting Oncogenic KRAS with Molecular Brush-Conjugated Antisense Oligonucleotides
Increasing the Throughput of Sensitive Proteomics by plexDIA
Local Mechanical Stimuli Correlate with Tissue Growth in Axolotl Salamander Joint Morphogenesis
Maximizing TLR9 Activation in Cancer Immunotherapy with Dual-Adjuvanted Spherical Nucleic Acids
Single-Dose Intra-Cartilage Delivery of Kartogenin Using a Cationic Multi-Arm Avidin Nanocarrier Suppresses Cytokine-Induced Osteoarthritis-Related Catabolism
Regenerating Axolotl Retinas Regrow Diverse Cell Types with Modulation by Notch Signaling and Reconnect to the Brain
Exploring Functional Protein Covariation across Single Cells Using nPOP
Wnt Signaling Coordinates the Expression of Limb Patterning Genes During Axolotl Forelimb Development and Regeneration
A Constitutively Expressed Fluorescence Ubiquitination-Based Cell Cycle Indicator (FUCCI) in Axolotls for Studying Tissue Regeneration

2021

Development of Fluorescently Labeled, Functional Type I Collagen Molecules
Interstitial Flow Enhances the Formation, Connectivity, and Function of 3D Brain Microvascular Networks Generated within a Microfluidic Device
Regeneration and Assessment of the Endothelial Glycocalyx To Address Cardiovascular Disease
Mild Repetitive Head Impacts Alter Perivascular Flow in the Midbrain Dopaminergic System in Awake Rats
Quantitative Imaging of Blood-Brain Barrier Permeability Following Repetitive Mild Head Impacts
High-Throughput Microfluidic 3D Biomimetic Model Enabling Quantitative Description of the Human Breast Tumor Microenvironment
Injectable Lignin-co-Gelatin Cryogels with Antioxidant and Antibacterial Properties for Biomedical Applications
Bottlebrush Polymer-Conjugated Melittin Exhibits Enhanced Antitumor Activity and Better Safety Profile
Two-Photon Peak Molecular Brightness Spectra Reveal Long-Wavelength Enhancements of Multiplexed Imaging Depth and Photostability
Stiffening of the Extracellular Matrix is a Sufficient Condition for Airway Hyperreactivity
Biomaterials and Oxygen Join Forces to Shape the Immune Response and Boost COVID-19 Vaccines
Imaging in vivo Acetylcholine Release in the Peripheral Nervous System with a Fluorescent Nanosensor
A DNA-Based MRI Contrast Agent for Quantitative pH Measurement
Confocal Imaging Capacity on a Widefield Microscope Using a Spatial Light Modulator
Lung Injury in Axolotl Salamanders Induces an Organ‐Wide Proliferation Response

2020

3D Visualization of Macromolecule Synthesis
Self-Assembled DNA–PEG Bottlebrushes Enhance Antisense Activity and Pharmacokinetics of Oligonucleotides
High-Power Light-Emitting Diode Array Design and Assembly for Practical Photodynamic Therapy Research
Engineering Bacillus subtilis as a Versatile and Stable Platform for Production of Nanobodies
Optical Nanosensors for in vivo Physiological Chloride Detection for Monitoring Cystic Fibrosis Treatment
Site‐Specific Bioconjugation and Convergent Click Chemistry Enhances Antibody–Chromophore Conjugate Binding Efficiency
Real-Time Particle-by-Particle Detection of Erythrocyte-Camouflaged Microsensor with Extended Circulation Time in the Bloodstream
Multichannel Correlation Improves the Noise Tolerance of Real-Time Hyperspectral Microimage Mosaicking
Our facility

Interdisciplinary Science and Engineering Complex

ISEC 080, 805 Columbus Ave, Boston, MA, 02115