Zeiss LSM 800

Our microscopy facility features cutting-edge confocal laser scanning microscopes with Airyscan from Zeiss. Our goal is to advance the research of the Boston community by offering competitive pricing and expertise.

Application Forms

Instrument Snapshot

The Zeiss LSM 800 is a compact confocal laser scanning microscope for high-end confocal imaging. This model has increased image quality, higher image output, and allows for easy imaging of live cells.

This confocal microscope has been used for a wide range of scientific applications from live cell culture imaging to model organisms, such as C. elegans and zebra fish. Paired with Airyscan module, images are 1.7 higher in resolution and sensitivity than compared to other scopes of this type.

Low laser powers avoid photobleaching and phototoxicity in live cell imaging applications.

Reach out to our core facility in Boston with any questions at cils-core@northeastern.edu.

Features

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Laser line: 405, 488, 561, 640 nm

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Objective: 10×20×40×63×

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Fixed cell/tissue imaging

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Image Tiling

N

Airyscan

Sample Images

Brain Microvascular Network

Instrument: Zeiss LSM 800
Brain endothelial cells: dTomato (red). Pericytes: NG-2 (purple). Astrocytes: GFAP (green)
Credit: Max Winkelman/Dai Lab

SARS-CoV-2 RBD & N Proteins

Instrument: Zeiss LSM 8oo confocal
In polymer walls of oxygen-generating COVID-19 cryogel-based vaccine
Credit: Colombani Thibault/Bencherif Lab

Cultured Microvascular Networks

Instrument: Zeiss LSM 8oo confocal
Formed under static and flow conditions within a 3D fibrin matrix
Credit: Max Winkelman/Dai Lab

Rates

Internal NU

$30/hr

External Academia

$50/hr

Industry

$70/hr

Additional Resources

Carl Zeiss Microscopy Online Campus

Education in Microscopy and Digital Imaging

ZEISS LSM 800 Manual

Applications, system, technology and details

ZEISS LSM 800 for Materials

Your Versatile Confocal Microscope for Research and Failure Analysis

Other Instruments

Zeiss LSM 880

Zeiss LSM 880 (Inverted)

NU user: $50/hr; Academia: $70/hr; Industry: $90/hr

Laser line: 405, 458, 488, 514, 561, 594, 640 nm

Objective: 10×20×40×40×63×

Cage incubator, CO2/O2 control

Superresolution (Airyscan)

Spectral Unmixing

Zeiss Axiozoom V16 (Upright)

NU user: $20/hr; Academia: $30/hr; Industry: $40/hr

Continuous zoom with high NA

Large field of view

Apotome.2 Structured Illumination Module

In vivo and model organism imaging

Zeiss Axio Observer (Demo, Inverted)

NU user: Free

Epifluorescence: DAPI, GFP, DsRed, Cy 5

Objective: 10×, 20×, 40×, 63×, 100×

Immunofluorescence labeled tissue or cell culture imaging

Our facility

Interdisciplinary Science and Engineering Complex

ISEC 080, 805 Columbus Ave, Boston, MA, 02115